Hypernatremia
Hypernatremia is high sodium in the blood that occurs with excessive fluid loss. When fluid is lost and not replaced, sodium is not adequately excreted from the body.
The following are causes:
- Diabetes insipidus (caused by deficiency of or insensitivity to ADH)
- Diarrhea
- Diuretic medication
- Excessive salt intake
- Excessive vomiting
- Heavy respiration (e.g., exercise, exertion)
- Severe burn
- Sweating
It is associated with the same symptoms as hyponatremia, and also causes the following:
- Delerium
- Irritability
- Muscle twitching
Hypernatremia commonly affects older hospitalized people, 50% of whom have underlying diseases that, when combined with excessive sodium and fluid loss, are fatal.
Treatment
Treating hypernatremia involves slowly replenishing water loss, usually over 48 hours, through drinking or intravenous (IV) solution. In cases of diabetes, the imbalance is treated with adequate water intake and nonsteroidal anti-inflammatory drugs or with synthesized hormones (e.g., desmopressin) that aid in fluid retention and decrease urination.
Some drugs used to treat electrolyte imbalance may be unsafe for pregnant women and should not be taken before consulting a physician.
Physician-developed and -monitored.
Original Date of Publication: 01 May 2001
Reviewed by: Stanley J. Swierzewski, III, M.D.
Last Reviewed: 04 Dec 2007
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